Royal jelly is a nutritious food that is produced by bees by consuming plenty of pollen and honey and by secreting it from their hypopharyngeal glands. Worker bees use royal jelly to feed queen bee and its babies. It used immediately at the time of secretion and is not stored. The larva, which is planed to be the queen bee, is fed with 25 times more royal jelly compared to a worker bee larvae. In commercial royal jelly production, queen bee cells are placed in the hives using a frame and larvae are transferred and larvae inside queen bee cells, which are candidates for queen bee, are fed with royal jelly. Young worker bees secrete royal jelly into honeycomb cells but the larvae don’t consume all royal jelly at once and royal jelly accumulates inside honeycomb cell. Queen bee honeycomb cells that contain the highest amount of royal jelly are taken from the hive and then larvae is taken out of the cell and royal jelly is collected. This is usually the common method for commercial royal jelly production. Body weight of the queen larva increase 1300 folds in 6 days due to excessive royal jelly consumption.